sclerosing glomerulonephritis

Only some children with RPGN ( 24.0 % ) were diagnosed as non_CGN according to the pathological findings including diffuse endocapillary proliferative glomerulonephritis , lupus nephritis type IV , proliferative sclerosing glomerulonephritis and focal segmental glomerulonephritis .

部分（24.0%）急进性肾炎的肾脏病理为非新月体肾炎，包括毛细血管内增生性肾小球肾炎、Ⅳ型膜增殖性狼疮性肾炎、增生硬化性肾小球肾炎及局灶节段性肾小球硬化；

Conclusion In patients with nephritic syndrome excepted sclerosing glomerulonephritis , TWP + PRE can improve the clinic effect and reduce the adverse reactions .

结论在病理除外硬化性肾小球肾炎的肾炎综合征患者中，TWP+PRE可提高临床疗效，减少药物副作用的发生。

Proliferative sclerosing glomerulonephritis and crescentic glomerulonephritis 3 cases ( 2.7 % ) each ;

新月体肾炎及增生硬化性肾炎各3例（2.7%）；

Conclusion Recombinant antisense TGF-B1 adenovirus inhibits synthesis and secretion of extracellular matrix in mesangial cells which may be effective in gene therapy for proliferative glomerulonephritis and sclerosing glomerulonephritis .

结论重组反义TGF-β1可抑制系膜细胞合成细胞外基质，在肾小球肾炎及肾小球硬化的研究及治疗中有潜在的应用价值。

[ Conclusion ] Recombinant TGF - β 1 antisense eukaryotic expression vector can inhibit the secretion of FN and PAI-1 , which may be effective in gene therapy for sclerosing glomerulonephritis and proliferative glomerulonephritis .

结论反义TGF-β1基因真核表达载体可从分子水平阻断MsC的FN及PAI-1表达，在肾小球硬化及肾小球肾炎的研究治疗中有一定的应用价值。

Results Chronic nephritis ( 39.3 % ) is the most common clinical type in the gerontic and gerontic early days idiopathic IgA nephropathy , and sclerosing glomerulonephritis ( 35.7 % ) is the most common pathological type ;

结果老年及老年前期原发性IgA肾病的临床类型主要以慢性肾炎最常见（39.3%），病理类型主要以硬化性肾小球肾炎（SGN）最常见（35.7%）；